| 1947 – 1951 | Liaqat Ali Khan | Muslim League |
| 1951 – 1953 | Khawaja Nazimuddin | Muslim League |
| 1953 – 1955 | Mohammad Ali Bogra | Muslim League |
| 1955 – 1956 | Ch. Mohammed Ali | Muslim League |
| 1956 – 1957 | Hussain Shaheed Suharwardi | Awami League |
| 1957 -1957 oct. nov. dec | Ibrahim Ismail Chaundrigar | Muslim League |
| 1957 -1958 | Malik Feroz Khan Noon | Republican Party |
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| 1971 midlertidig ledelse | Noor-ul-Amin | Muslim League |
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| 1973 – 1977 | Zulfiqar Ali Bhutto | Pakistan People party |
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| 1985 – 1988 | Muhammad Khan Junejo | |
| 1988 – 1990 | Benazir Bhutto | Pakistan People Party |
| 1990 – midlertidig ledelse | Ghulam Mustafa Khan Jatoi | |
| 1990 – 1993 | Mohammed Nawaz Sharif | Muslim League |
| 1993 midlertidig ledelse | Balakh Sher Mazari | |
| 1993 – 1993 – maj, juni og juli | Mohammed Nawaz Sharif | Muslim League |
| 1993 midlertidig ledelse | Moeenuddin Ahmad Qureshi | |
| 1993 – 1996 | Benazir Bhutto | Pakistan People Party |
| 1996 – 1997 midlertidig ledelse | Malik Meraj Khalid | |
| 1997 – 1999 | Mohammed Nawaz Sharif | Muslim League |
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| 2002 – 2004 | Zafarullah Khan Jamali | Muslim League |
| 2004 midlertidig ledelse | Chuadhary Shujaat Hussain | Muslim League |
| 2004 – 2007 | Shaukat Aziz | Muslim League |
| 2007 – 2008 midlertidig ledelse | Muhammad Mian Soomro | |
| 2008 – 2012 | Syed Yousaf Raza Gillani | Pakistan People Party |
| 2012 – 2013 | Raja Pervez Ashraf | Pakistan People Party |
| 2013 midlertidig ledelse | Hazar Khan Khoso | |
| 2013 – 2017 | Muhammad Nawaz Sharif | Muslim League |
| 2017 – 2018 | Shahid Khaqan Abbasi | Muslim League |
| 2018 midlertidig ledelse | Nasir-ul-Mulk | |
| 2018 – 2022 | Imran Khan | Pakistan Tehreek-e-Insaf |
| 2022 – ? | Muhammad Shehbaz Sharif | Muslim League |
